In fact there is a major problem with a nomad civ :
if they leave solar systems, others will colonize them and they won't be able to come back
at the end of the game there will be no more available solar systems (or the galaxy is enough big and impossible to colonize at 100%)
Nomads will just have poor systems with only inhospitable planets at the end
But this problem could be part of the gameplay nomads could spread widely at the beginning but then have to settle in the middle of the game
They have to spread to maximize their trade or pirate abilities
if they choose the pirate way they could hide in inhospitable systems and move to an other when they are attacked the fact that the systems is poor is not a problem as their incomes come mainly from piracy (poor system ensure only a minimum income)
If they choose the trade way they could settle in more interesting systems but if they choose very interesting systems others will be tempt to military drive them out and they are weak... So they could first take the most interesting systems and then leave to other systems, less interesting, when other players came in the area it could be part of a negotiation.