As a kid I was heavily impressioned by the alternate timeline Enterprise D
 
 
  

It was able to break the Warp 10 barriar and equiped with a cloaking device.  
I always thought it looked awesome.  Even more than it actually does.  (I saw it when I was maybe 10, and had not seen it again until less than a year ago... surprised to see it actually played a smaller part than I remembered)
 
Other than that, I think I like Ferengi ships.  They seem the most realistic.
I have a soft spot for 24th century Klingon ships, the command ships in particular, mostly because I built a model of one as a kid.  Romulan ships confuse me.  Their structure doesn't make any sense to me.  I thought Dominion ships (DS9) look pretty awesome too.